This project is to develop clinical positioning devices to further the development of Digital Tomosynthesis applications emphasizing studies of the Vasculature of the brain. In collaboration with two consultants, one from the Department of Radiology, University of Mississippi, and one from the University of Virginia, Kermath proposes to use experience gained from previous design of conventional L-C positioning devices that employed conventional tomographic capabilities and L-C positioning devices that are currently supporting Digital Vascular Imaging (D.V.1.) devices to produce the subject hardware.The two consultants have designed and built two D.V.1. systems which will be used, -together with the L-C positioning devices at the University of Mississippi and the University of Virginia which will serve as clinical evaluation sites. These D.V.I. systems will employ tomosynthesis applications (a method of tomography, employing a number of fixed exposures and manipulation by an Image Processor).While current literature supports the need for digital, tomography, the only available positioning hardware is the test-bench variety and is not suitable for clinical usage. Kermath proposes to develop and furnish clinical hardware to complement the required D.V.1. motion and attitude requirements.National Institute of Mental Health