SBIR-STTR Award

A Novel, Membrane-Based Bioreactor Design to Enable a Closed-Loop System on Earth and Beyond
Award last edited on: 6/23/2022

Sponsored Program
STTR
Awarding Agency
NASA : ARC
Total Award Amount
$873,153
Award Phase
2
Solicitation Topic Code
T6.04
Principal Investigator
Allison Pieja

Company Information

Mango Materials

1400 Radio Road
Redwood City, CA 94065
   (650) 427-0430
   info@mangomaterials.com
   www.mangomaterials.com

Research Institution

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Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
2016
Phase I Amount
$123,164
The proposed innovation is a membrane bioreactor system to produce a biopolymer from methane gas. This new methane fermentation process will expand and advance current gas delivery techniques to create affordable fermentation methods on Earth and beyond. Mango Materials is currently working to scale up and commercialize the production of polyhydroxyalkanoate (PHA) from methane, but its scaled-up fermentation systems are typically tall and narrow to take advantage of hydrostatic pressure for the transfer of methane into solution. The proposed work represents a unique approach that could enable the production of biopolymer on Earth and also non-Earth environments, thus creating a closed-loop system for producing biopolymer products on-demand in outer space. The proposed design is a novel, membrane-based bioreactor that will enable bacterial growth and biopolymer production to occur in microgravity environments on moist membranes that are sandwiched between layers of the gaseous feedstocks methane and oxygen. This system will allow for efficient energy use, minimal square footage, and effective mass transfer from the gaseous to the liquid phase without being dependent on hydrostatic pressure. Mango Materials will partner with Colorado School of Mines where there is extensive experience with membrane bioreactors, to design and construct this system.

Potential NASA Commercial Applications:
(Limit 1500 characters, approximately 150 words) Use of membrane bioreactor (MBR) systems to enable production of various methane fermented products such as polyhydroxyalkanoates (PHAs) for use in many plastic-like applications, nutritional supplements, essential amino acids, bioremediation, and products for advanced life support. For example, sustainable polyhydroxyalkanotes (PHAs) can be produced and formed into filaments that could be used for 3-D printing applications on the International Space Station (ISS). Also, this MBR system and ultimate PHA production will contribute to the resource recovery and waste processing goals of advanced life support at NASA.

Potential NON-NASA Commercial Applications:
(Limit 1500 characters, approximately 150 words) Polyhydroxyalkanoates (PHAs) are a substitute for conventional plastic goods including microbeads, packaging, childrens� toys, electronic casings, coatings, and agricultural films. These materials can be fully biodigestable and will be converted back into carbon using microbial processes. This carbon can enter the natural carbon cycle and prevent additional carbon to affect the atmospheres of Earth or other planetary bodies. PHAs are also fully edible and can be digested by humans safely.

Technology Taxonomy Mapping:
(NASA's technology taxonomy has been developed by the SBIR-STTR program to disseminate awareness of proposed and awarded R/R&D in the agency. It is a listing of over 100 technologies, sorted into broad categories, of interest to NASA.) Biomass Growth Biophysical Utilization Coatings/Surface Treatments Essential Life Resources (Oxygen, Water, Nutrients) Food (Preservation, Packaging, Preparation) In Situ Manufacturing Organics/Biomaterials/Hybrids Polymers Processing Methods Smart/Multifunctional Materials

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
2017
Phase II Amount
$749,989
The proposed innovation is a membrane bioreactor system to produce a biopolymer from methane gas that is applicable in outer space environments. This new methane fermentation process will expand and advance current gas delivery techniques to create affordable fermentation methods on Earth and beyond. Mango Materials is currently working to scale up and commercialize the production of polyhydroxyalkanoate (PHA) from methane, but its scaled-up fermentation systems are typically tall and narrow to take advantage of hydrostatic pressure for the transfer of methane into solution. The proposed work represents a unique approach that could enable the production of biopolymer on Earth and also non-Earth environments, thus creating a closed-loop system for producing biopolymer products on-demand in outer space. The proposed design is a novel, membrane-based bioreactor that will enable bacterial growth and biopolymer production to occur in micro- or low-gravity environments by providing gases through membranes. Growth and biopolymer production using methane as a feedstock will be demonstrated at high efficiencies. The proposed work will also identify methods by which process wastes can be recycled back to minimize the required inputs. Finally, a thorough feasibility analysis will be conducted to evaluate the use of the process on a long-term space mission. Mango Materials will partner with Colorado School of Mines, where there is extensive experience with membrane bioreactors, to design and construct this system.

Potential NASA Commercial Applications:
(Limit 1500 characters, approximately 150 words) Use of membrane bioreactor (MBR) systems to enable production of various methane fermented products such as polyhydroxyalkanoates (PHAs) for use in many plastic-like applications, nutritional supplements, essential amino acids, bioremediation, and products for advanced life support. For example, sustainable PHAs can be produced and formed into filaments that could be used for 3-D printing applications on the International Space Station (ISS). Also, this MBR system and ultimate PHA production will contribute to the resource recovery and waste processing goals of advanced life support at NASA.



Potential NON-NASA Commercial Applications:
:

(Limit 1500 characters, approximately 150 words) Polyhydroxyalkanoates (PHAs) are a substitute for conventional plastic goods including microbeads, packaging, childrens? toys, electronic casings, coatings, and agricultural films. These materials can be fully biodigestable and will be converted back into carbon using microbial processes. This carbon can enter the natural carbon cycle and prevent additional carbon to affect the atmospheres of Earth or other planetary bodies.

Technology Taxonomy Mapping:
(NASA's technology taxonomy has been developed by the SBIR-STTR program to disseminate awareness of proposed and awarded R/R&D in the agency. It is a listing of over 100 technologies, sorted into broad categories, of interest to NASA.) Biomass Growth Biophysical Utilization Coatings/Surface Treatments Composites Food (Preservation, Packaging, Preparation) Organics/Biomaterials/Hybrids Polymers Waste Storage/Treatment