SBIR-STTR Award

Biological systems rely upon DNA for identity, indeed, for every aspect of innate function. We utilized botanical genomes as primary DNA source and engineered unique biological markers of SC originality, verifiable anywhere in the supply chain. Formulation stabilizes the marks against the challenges of SC manufacturing and the physicochemical environs that SCs experience. The sensitivity of DNA detection requires infinitesimal quantities of DNA to adequately mark SCs; there is no impact upon manufacturing. There are no limits to the number of unique markers that can be designed, or the quantity of DNA manufactured. Association of the DNA mark with reporter groups allows for rapid screening to detect the presence of DNA markers. When suspicions are elevated, forensic DNA analysis from a simple SC swab can prove originality beyond all doubt. Preliminary results from “Red Team Challenges” support our claim that these marks cannot be copied. This study extends our observations obtained while embedding DNA in the epoxyacrylate inks used to mark SC. We will develop a library of >10,000 marks, extending these marks into new ink formulations and commercial methods of marking in large scale. We will extend our early work on non-ink embedment methods. Stability challenges will be extended.

Keywords:
Ensuring military supply chain security using botanical DNA Marking components with unique botanical DNA, Avoidance of counterfeit parts using botanical DNA authentication

Applied DNA Sciences (APDN) has developed a reliable DNA-optical adduct that is impervious to copying and is required by the Defense Logistic Agency (DLA) for the marking of FSC 5962 electronic components. Commercial inks supplemented with optical markers and proprietary APDN DNA, trademarked SigNature® DNA, ink provide authentication marks that are of a higher standard relative to other taggant technologies. The proposed research project detailed herein would expand the scope and scale of production of the existing technology platform established in the Phase I SBIR to accommodate as many as 100 component manufacturers. In addition to developing more efficient methods of SigNature® DNA application, the proposed research entails the development and construction of an optical reader that could be employed in the field for rapid detection of the SigNature® DNA ink marked on a component. Furthermore, in Phase II, the minimal amount of APDN DNA, optical markers, and ink necessary to maintain efficient detection by existing forensic and visual techniques would be investigated and validated. Approved for Public Release 14-MDA-7739 (18 March 14).

Keywords:
DNA, Applied DNA Sciences, Signature® DNA, optical markers, printing, commercialization, detector