SBIR-STTR Award

Rapid Processing of Positioning Information for Hand-Held Gamma Camera
Award last edited on: 10/31/03

Sponsored Program
SBIR
Awarding Agency
DOE
Total Award Amount
$698,238
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Irving N Weinberg

Company Information

Naviscan Inc (AKA: PEM Technologies Inc~Naviscan PET Systems Inc)

6865 Flanders Drive Suite B
San Diego, CA 92121
   (858) 587-3641
   service@naviscan.com
   www.naviscan.com
Location: Multiple
Congr. District: 52
County: San Diego

Phase I

Contract Number: DE-FG02-99ER82852
Start Date: 00/00/00    Completed: 00/00/00
Phase I year
1999
Phase I Amount
$99,805
Surgeons prefer to use nonimaging gamma probes for intraoperative work instead of conventional, gantry-held, large field-of-view gamma cameras. Unfortunately, the nonimaging gamma probes are of limited assistance in regions of the body with complex three-dimensional anatomy (e.g., head and neck, axilla). This project will develop a low-cost, hand-held gamma camera, which could improve lesion contrast. Modified backprojection algorithms will be applied to achieve nearly real-time imaging with novel, gantry-less hardware architectures. Phase I will build a prototype, hand-held gamma camera with software that integrates gamma ray acquisition data with gantry-less positioning information. Using hot spot phantoms and mototorized positioners to simulate a human operator with no training on the device, the performance of the prototype camera will be compared to conventional planar gamma cameras.

Commercial Applications and Other Benefits as described by the awardee:
The product promises to improve on the performance of nonimaging probes without significantly increasing cost. This work also should spur further development of deployable intraoperative gamma camera architectures.

Phase II

Contract Number: DE-FG02-99ER82852
Start Date: 00/00/00    Completed: 00/00/00
Phase II year
2000
Phase II Amount
$598,433
Medical and industrial users of noninvasive radiation detection technology want improved contrast and depth information to better visualize subtle abnormalities. This project will improve the detection and characterization of radioactive sources employed in surgery. The improvement can be achieved cost-effectively through novel sensor technologies and appropriate algorithms. In Phase I, a working human-directed imaging device was constructed. Enhanced contrast of the radioactive sources was demonstrated, compared to conventional cameras. The Phase II project will develop algorithms to improve real-time performance, modify the hardware for intra-operative use, conduct clinical trials to validate the technology, and examine novel applications for radioactive waste detection.

Commercial Applications and Other Benefits as described by the awardee:
The product is aimed at the robust and growing intra-operative visualization market. A potential Phase III partner has been identified for both medical and industrial applications.