A SMART Life Science prototype that facilitates the management of instrumentation data has far reaching implications. As much as the benefit is to an individual scientist, the greater impact affects the entire economy by facilitating the rapid launching of new scientific discoveries that cure disease and product new economic channels for firms. By improving process efficiencies in R&D organizations, SMART research environments will greatly improve the competitiveness of US firms by clearing the administrative barriers associated with innovation. COMMERCIAL APPLICATIONS: SMART technologies can have a strong impact on improving researcher productivity by providing advanced and accurate metadata based knowledge frameworks and ontologies; facilitating workflows that reduce the amount of time spent on identifying community efforts; and providing evolvable interfaces that allow for individual preference in searching, annotating and publishing results to the scientific community