The Department of Homeland Security (DHS) requires an affordable anomaly detection device for non-destructive inspection to determine if perceived hollow spaces are empty or densely packed with contraband. DHS has identified a need to detect narcotics, weapons, explosives or other contraband smuggled over the border, onto planes, or carried into public venues while concealed in hollow spaces such as bicycle, stroller, or wheelchair frames. In response to these requirements ESA proposes to develop the Contraband Element Imager Technology (CEE-IT), a safe, hand-held, low-dose x-raybased sensor imaging system. The significance of this innovation is the use of portable, hand-held, medical x-ray real-time imaging technology that can be used to image the contents of hollow spaces while utilizing software to key on the various densities of materials to quickly identify and create images and identities of the contents. The advantage of the CEE-IT innovation is that it enables DHS to detect and identify contraband during primary screening and virtually eliminates the secondary screening steps that disrupt normal flow through ports of entry. The successful development and integration of this technology at inspection points will allow quick, reliable and cost-effective non-destructive detection of concealed contraband with minimal disruption to normal commerce operations and without compromising the safety of our nation. Potential applications for the CEE-IT innovation include DoD checkpoints and installations, critical infrastructure security (utilities, transportation, shipping), public event security, and building security.