First Responders face critical life and death issues in dangerous environments. Efficient radio communications is essential in the success of their mission, but high background noise can degrade radio efficiency and intelligibility. This proposal presents a novel approach to mitigate noise, improve VOX efficiency, permit hands free operation, and improve voice intelligibility. It is based on the principle of adaptive noise cancellation. GL Communications Inc., Dr. Christopher Fuller, and Larry Lutz will team together to demonstrate the feasibility of a portable noise canceller that first responders can easily adapt to their current mobile radios and at relatively low cost. The team has a long track record in noise cancellation technology, product development, testing, and commercialization.This project is in response to the Department of Homeland Security Small Business Innovation Research (SBIR) Program solicitation of Topic Number H-SB09.2-006.