Current methods for blood sampling do not allow for remote self collection and maintenance of sample integrity during transport and storage is difficult. Spot On Sciences is developing a fast, simple to use device for remote, self-sampling and robust transport and storage of blood samples at ambient temperatures. Based on dried blood spot technology, HemaSpot (patent-pending) is a single use, all-in-one device that uses a finger stick to collect and dry blood within a protective cartridge. Portions of the sample can be immediately tested, shipped and/or stored in the HemaSpot cartridge for years. Additional advantages are less invasive sampling, small volumes, superior sample stability, and compatibility with common diagnostic test methods. In the current proposal, individual components of HemaSpot will be tested and optimized. Blood samples will be analyzed for a minimum of 2 analytes by mass spectrometry to demonstrate analyte stability and recovery. Ph II studies will include prototype manufacture and validation in larger-scale field studies toward our ultimate goal of commercializing the HemaSpot device for self blood sampling in clinical or remote settings for routine diagnostic testing.
Keywords: Dried Blood Spot, Remote Blood Sample Collection, Mass Spectrometry, Cortisol, Oxycodone, Oxymorphone, Testosterone, Insulin
