SBIR-STTR Award

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Development of Naked DNA Vaccine: Brucella
Award last edited on: 4/3/2002

Sponsored Program
SBIR
Awarding Agency
DOD : CBD
Total Award Amount
$70,000
Award Phase
1
Solicitation Topic Code
CBD99-106
Principal Investigator
Ales Prokop

Company Information

Nanodelivery Inc

5123 Virginia Way Suite C-21
Brentwood, TN 37027
   (615) 221-9022
   F.Baudenbacher@Vanderbilt.edu
   N/A
Location: Single
Congr. District: 07
County: Williamson

Phase I

Contract Number: ----------
Start Date: ----    Completed: ----
Phase I year
1999
Phase I Amount
$70,000
This Phase I Proposal aims to maximize gene transfer by means of polymeric-based micellar and nanoparticulate delivery vehicles in order to elicit protective immunity against Brucella. In-vitro cell mediated cytotoxicity and in-vivo pathogen protection in a challenge test will be demonstrated. For Phase I Option we will further characterize the protective immunity by means of cellular and humoral responses and analyze the protective effect over an extended period of time.

Benefits:
Development of protective (and therapeutic) vaccine against Brucella as a commercial product

Keywords:
Polymeric Nanoparticle Cell-Mediated Cytotoxicity Humoral Cellular Responses Low Regulatory Burden P

Phase II

Contract Number: ----------
Start Date: ----    Completed: ----
Phase II year
----
Phase II Amount
----