Robust entanglement of spatially separated particles or ensembles of particles is an enabling technology for quantum networking, quantum communication, and quantum information processing. While a variety of platforms have supported demonstrations of this type of entanglement, room-temperature atomic vapor cells are a particularly attractive implementation because of the relative simplicity of the technology involved, requiring no cryogenics or vacuum systems, and with very modest laser requirements. AOSense proposes to combine recent advances in quantum measurement with our expertise in engineering vapor-cell systems to demonstrate a quantum networking architecture based on room-temperature vapor cells.