The collection, analysis, objective evaluation, and aggregation of pilot physiological data provides a unique opportunity to support emerging Air Force human performance and wellness optimization programs. This data can provide better insights and inform treatment decisions to improve the effectiveness of such programs, while also providing a unique and personalized approach for each fighter pilot. TITUS's SPEAR® Enterprise Data System and Design Interactive's (DI) biosignature analytics classifiers can each be modified and integrated to create a customized, best-in-class human performance monitoring tool for capturing, measuring, and making sense of a wealth of fighter pilot human performance data. The result will be personalized and predictive information that allows wellness and healthcare providers to make more appropriate interventions and therapies more quickly, resulting in improved health and pilot longevity