Actively involved in SBIR when the firm was much younger, in May 2016, Biomedical Enterprises was acquired DePuy Orthopaedics, Inc., part of the DePuy Synthes Companies of Johnson & Johnson and is now functioning as a subsiduary, BioMedical Enterprises, Inc. (BME), had been a manufacturer of Nitinol orthopaedic implants for small bone fixation. The implants are used to treat bunions, hammertoes and other foot and ankle deformities, as well as hand and wrist deformities. The BME acquisition reinforces Johnson & Johnson Medical Devices focus on accelerating meaningful innovation and strengthening DePuy SynthesÂ’ portfolio for elective extremity procedures - providing a more complete solution for foot and ankle and hand and wrist specialists. BME was among the first U.S. manufacturers of Nitinol metal implants for musculoskeletal fixation and is a market leader in the use of memory metal implants for bone fixation. Nitinol is a nickel-titanium alloy that provides dynamic continuous active compression, which helps to promote healing after bone fixation. BME implants come ready-to-use on a sterilized, pre-loaded, fully disposable insertion tool. BioMedical Enterprises, Inc. (BME) began as a privately held medical device company providing musculoskeletal research service to pharmaceutical, biotechnology, and orthopaedic industries working closely with leading teaching institutions and some of the worldÂ’s largest orthopaedic companies on various bone healing research projects. Over time BME entered the medical device market searching for products that would help bones heal faster and better. Through collaborations with a worldwide network of research and innovation, BME was introduced to memory metal compression bone staples and soon became the first to market heat-activated shape memory devices in the United States. Taking the concept one step further BME develop the ability to control the compressive forces these implants exert to make the system suitable for a variety of applications under varying degrees of bone qualities. The firm created and patented the OSSforceTM Implant Controller bringing all manufacturing activities in-house to ensure the best quality control possible while protecting intellectual property. BME evolved into a Reconstructive Bone Fusion product company with a comprehensive line of shape memory bone fusion implan