We have developed a technology to efficiently produce high quality personalized audio cassette tapes. We will use this technology to test the clinical efficacy of a prototype personalized childhood asthma self-management program. Program objectives include determining how well such a personalized self-care system can improve a child's ability to1) predict and self-control personal asthma triggers;2) remember and initiate prescribed treatment;3) determine the best response to given stimuli;4) self-control behavioral and psychological consequences relevant to his/her asthma;5) relax and perform breathing routines when necessary.The principal outcomes expected from a successful Phase I test include1) children require less personal training time from health professionals;2) improved compliance with medical regimens;3) fewer missed school days and emergency room visits;4) relief from fear and anxiety;5) less alienation from family, medical staff and other children.Key project tasks include defining what data is most relevant for a personalized program and the most appropriate ways to collect and use personal information for improved self-management. A successful Phase I test will answer the following critical questions prior to Phase II:1) Are personalized learning programs demonstrably more effective than generic programs?2) Can the core technology quickly and efficiently produce large quantities of personalized audio tapes?National Heart, Lung, and Blood Institute (NHLBI)