The long term objective of this line of investigation is to develop a new class of antivirals which are effective against a wide variety of infections, are safe for human use, economical to produce and enhance resistance to or recovery from viral infectious agents. The agents may have application in conjunction with known immunopotentiators recent experimental data indicate that a variety of common organic and inorganic compounds possess decided antiviral properties and constitute a potentially important class of antiviral agents. The data indicate that these agents are effective both in vitro and in vivo. During phase i, matrix will conduct tissue culture and preliminary intact animal studies of the prophylactic and therapeutic efficacy of four of the most promising compounds against respiratory, influenza and encephalitis viruses.
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