SBIR-STTR Award

This project will explore the development of an advanced, low-cost computer system, based on a virtual-memory Intel 80386 processor, for image analysis, graphical data storage, and threedimensional reconstruction that will be used as a neuroanatomical workstation. The station will include provisions for data input from a digitizing tablet, computer microscopy using a light microscope with stepper motor stage, and autoradiography analysis with a video camera and light box. A modeling and reconstruction package will feature solid-body graphical imaging, and a standardized database format will promote data archiving and exchange among a community of users.The aims of this project are: (1) to put existing software and test capabilities on a 80386based system, (2) to design future software development for a "neuroanatomist's notebook," and (3) to examine the feasibility of applying advanced system features and knowledge representation techniques for later development in Phase II.National Institute of Neurological and Communicative Disorders and Stroke (NINDS)

This Phase II project will continue the development of two advanced neuroscience and medical imaging workstations, one a low-cost system based on the virtual memory SUN-386 microcomputer and the other a high-performance system based on the SUN-4/260 Al workstation, for image analysis, graphical and textual data storage, three-dimensional reconstruction, and volume imaging. The workstations will include provisions for data input from a digitizing tablet, computer microscopy using a light microscope with stepper motor stage, autoradiography analysis with a video camera and light box, and computer tapes of computed tomography and magnetic resonance imaging data. The modeling and reconstruction package will feature solid-body graphical imaging, volume rendering and manipulation, and a standardized database format.The aims of this project are to:(1) port existing software and test capabilities on the SUN systems,(2) develop volume-imaging techniques as useful research and clinical tools,(3) develop software for a "neuroscientist's reference," and(4) promote the creation of a standard data exchange format for anatomical graphics.

Anticipated Results:
Biographics, Inc., will produce neuroscience and medical imaging workstations for individuals in research and clinical settings.National Institute Of Neurological Disorders And Stroke (NINDS)