Using proprietary AI, computational and experimental approaches of Synthetic Biology, the management of Biosynthetic Machines Inc - BSMI - is organized around the construction of organisms for microbiological production of chemicals. Management suggest that solution to complexities of organism construction is Accelerated Agnostic Strain Engineering (AASE) strategy, a modification of a generic Design-Built-Learn approach structured to rely on Machine Learning and combinatorial gene engineering developed by companys founders at Argonne National Laboratory. The approach is universal in nature and - as such - could dramatically expand the list of chemicals produced in biomanufacturing by eliminating its biggest bottleneck, slow and poorly predictable process of strain develop