Numerica proposes to develop a physics-based, real-time prototype battle management and advanced guidance algorithm that produces optimal launch scheduling and optimal guidance for mid-trajectory interception of hypersonic threats, thereby delivering more efficient and effective intercept performance than can currently be achieved using traditional guidance, navigation, and control methods. Differential game theory will be applied to develop advanced interceptor guidance for defense against maneuverable threats that actively attempt to evade the interceptor. An intelligent battle management component will support cooperative intercepts, optimal launch scheduling, and optimal interceptor-to-threat assignment. The system will be demonstrated in a robust modeling and simulation framework created by Numerica as part of this effort to support algorithm development, evaluation, and trade space analysis for the Phase I problem space. Government-furnished information, if available, will be used for evaluation in Phase II. Numerica will identify Federal programs of record and civilian use cases to which the technology (or components thereof) could be transitioned. Approved for Public Release | 21-MDA-11013 (19 Nov 21)