Based on novel human cells lyophilization and reconstitution technology, SPZ Technologies, LLC (aka SPZT) is indicated as developing a Human Cell-Based Biosensor (HCB) for water toxicant testing. As conceived, the HCB would use an electric cell-substrate impedance sensing (ECIS) technique and is composed of an ECIS chip and an ECIS reader. The assertion is that If made effectively operational, this approach w/could make the HCB device sensitive to all required toxicants in the desired sensitivity range. It would be portable, likely reasonably priced, assumed deasy to operate and to be shelf-stable for many months - perhaps up to 2 years - under variety of environmental conditions.