Company Profile

Precision Biosciences Inc
Profile last edited on: 11/2/2022      CAGE: 4L4Q1      UEI: NWW1HFV2RQU3

Business Identifier: Next generation gene editing technology
Year Founded
2006
First Award
2008
Latest Award
2010
Program Status
Inactive
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Location Information

302 East Pettigrew Street Suite A-100
Durham, NC 27701
Location: Single
Congr. District: 01
County: Durham

Public Profile

Spunout of Duke, Precision BioSciences, Inc. is a clinical stage biotechnology company developing and commercializing therapeutics and services based on genomic molecular biology and dedicated to improving life (DTIL) with its novel and proprietary ARCUS genome editing platform. ARCUS is a highly precise and versatile genome editing platform that was designed with therapeutic safety, delivery, and control in mind. Using ARCUS, the Company’s pipeline consists of multiple ex vivo “off-the-shelf” CAR T immunotherapy clinical candidates and several in vivo gene editing candidates designed to cure genetic and infectious diseases where no adequate treatments exist. The firm offers Biotherapeutics, a directed nuclease editor (DNE) therapeutic targeted to enable the in situ correction of genes responsible for human diseases; Biotools, an engineered DNE meganucleases used to engineer cell lines for disease models or optimize cell lines for the biomanufacturing of protein vaccines and therapeutics; and PlantSciences, a custom DNE meganucleases that enable site-specific engineering of row crops and biofuel feedstock. Precision’s proprietary ARCUS genome editing technology essentailly enables the production of highly specific nucleases that can insert, remove, and modify DNA at essentially any location in a complex genome. The firm went public (NASDAQ: DTIL) in May 2019

Extent of SBIR involvement

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Synopsis: Awardee Business Condition

Employee Range
150-249
Revenue Range
15M-20M
VC funded?
Yes
Public/Private
Publicly Traded
Stock Info
NASDAQ : DTIL
IP Holdings
100-149

Awards Distribution by Agency

Most Recent SBIR Projects

Year Phase Agency Total Amount
2010 1 NIH $161,036
Project Title: Genetic Engineering of Cell Lines for Bioproduction
2009 1 NIH $141,260
Project Title: Complete Mhc Sequencing Using Engineered Meganucleases
2008 1 NIH $100,000
Project Title: Correction of dF508 Cystic Fibrosis Using an Engineered Nuclease
2008 1 NIH $100,000
Project Title: JAK2 Gene Correction Using an Engineered Homing Endonuclease

Key People / Management

  Matthew Kane -- Founder, President and Chief Executive Officer

  Derek Jantz -- Founder, CSO, Vice President, Scientific Development

  Chelsea Lynam

  Todd Melby -- Chief Financial Officer/Chief Operations Officer

  Jeff Smith -- Co-Founder & CTO

  David S Thomson -- Chief Development Officer