
Development of a Wearable Fluorescence Imaging Device for IntraoperativeIdentification of Brain TumorsAward last edited on: 2/1/2024
Sponsored Program
STTRAwarding Agency
NIH : NCITotal Award Amount
$1,238,362Award Phase
2Solicitation Topic Code
394Principal Investigator
Guoqiang YuCompany Information
Biopticstechnology LLC (AKA: Bioptics Technology LLC)
2236 Barnwell Lane
Lexington, KY 40513
Lexington, KY 40513
N/A |
N/A |
N/A |
Research Institution
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Phase I
Contract Number: 1R41CA243600-01Start Date: 8/1/2019 Completed: 7/31/2020
Phase I year
2019Phase I Amount
$210,428Public Health Relevance Statement:
PROJECT NARRATIVE The goal of this STTR Phase-I project is to develop and commercialize an innovative low-cost, wearable, fluorescence imaging device that can be attached to the standard surgical eye loupes for helping neurosurgeons to easily and accurately identify brain tumors for safe and maximal resection. This wearable ergonomic device will result in a wide range of movement and fast/easy operation, thus providing a novel way to image fluorescing brain tumors without a large expensive operative microscope. The potential market size of this affordable device are tens of millions of dollars in the US alone, and potential customers are neurosurgeons working across a wide range of surgical units, especially at regional and mobile army surgical hospitals.
Project Terms:
Accounting; Area; base; Biopsy Specimen; Blinded; Blood - brain barrier anatomy; Brain Neoplasms; care costs; Clinical; Cognitive; Color; Color Visions; commercialization; contrast enhanced; Conventional Surgery; cost; Custom; Data; design; Detection; Development; Devices; Diagnosis; Dyes; Ensure; Excision; experience; Eye; FDA approved; flexibility; Fluorescein; Fluorescence; fluorescence imaging; fluorescence microscope; fluorescence-guided surgery; Goals; Gold; Halogens; Healthcare Systems; Hospitals; Hour; Image; Image-Guided Surgery; Imagery; Imaging Device; imaging system; Imaging Techniques; improved; innovation; Intracranial Neoplasms; Intravenous; Legal patent; Life; Light; light weight; Lighting; Magnetic Resonance Imaging; Malignant Glioma; Malignant neoplasm of brain; Malignant Neoplasms; Measurement; Microscope; miniaturize; Movement; Neurosurgeon; Normal tissue morphology; novel; Obstruction; off-patent; Operating System; operation; Operative Surgical Procedures; optical imaging; Optics; Outcome; Patients; Performance; performance tests; Phase; phase 1 study; phase 2 study; portability; Primary Brain Neoplasms; prototype; Psychological Impact; research and development; Running; safety and feasibility; Small Business Technology Transfer Research; Sports; Surgeon; surgery outcome; Surgical margins; Survival Rate; System; Techniques; Technology; Testing; Time; Training; tumor; Tumor Tissue; United States; Universities; Video Recording; wearable device; Work
Phase II
Contract Number: 2R42CA243600-02Start Date: 9/25/2023 Completed: 8/31/2025
Phase II year
2023Phase II Amount
$1,027,934Public Health Relevance Statement:
PROJECT NARRATIVE Fluorescent imaging of cancers during surgery allows real-time cancer-specific detection for guiding tumor removal, often resulting in significant improvements in patient survival; however, it is hampered by large expensive equipment. Bioptics Technology (BOT) is developing an innovative, low-cost, wearable fluorescence imaging device (FLoupeâ¢, BOT brand) that attaches to standard surgical eye loupes to help neurosurgeons easily and accurately identify brain tumors for safe and maximal removal. This affordable and wearable device will significantly increase the ability of more surgeons to conduct fast and thorough operations, and thus improving patient safety and outcomes.
Project Terms:
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