Headed up by a key player and leader in the Center for Technology and Behavioral Health at Dartmouth, Square2 Systems is anchored in two decades years of research in computer-assisted, self-directed behavior change. The firm is using evidence-based techniques to tackle tough problems with behavioral components -- issues like addiction, anxiety, depression, and chronic disease. Apps are being developed using proven interventions like cognitive behavior therapy to enable people not only with recovery, but also with problems like depression and pain that accompany substance abuse. In randomized trials, people who used it had higher rates of abstinence and were more likely to stay in a recovery program than those in the control group