SBIR-STTR Award

Successfully reaching and enrolling fully representative target populations in public health interventions is a highly desired, but notoriously difficult, prospect, especially when an initiative is focused on socially charged issues or health conditions that affect vulnerable subgroups. For example, HIV/AIDS has disproportionately high morbidity among a number of minority/marginalized populations, and faces a stigma that further complicates recruitment efforts. The commercial sector, on the other hand, faces similar challenges for engaging diverse audiences, but has achieved highly notable successes in its marketing and advertising efforts. Brands and companies have effectively utilized a number of innovative approaches to increase operational efficiency, measure campaign effectiveness, and capture relevant data to pinpoint specific consumer behavior. A comparable approach, tailored to meet the idiosyncratic needs of the public health enterprise, would offer significant improvement to its ability to engage with intended audiences. Those proven methods, however, entail significant capital and dedicated personnel that are not typically available to the majority of public health organizations. Thus, there is a pronounced yet unmet need for more scalable toolsets that can improve outreach and engagement of target populations. In order to address these challenges, this project seeks to increase representative enrollment through customized outreach analyses and informed tailoring of recruitment and engagement strategies. The proposed web-based system will enable researchers to conduct typology stratification of participant groups based on demographic, psychographic, and other pertinent characteristics, and will provide a platform for iterative improvement toward encouraging desired enrollee behavior in real-time. This targeted approach holds the promise to enhance participant engagement in public health interventions, and will be tested in the context of facilitating enrollment in an eHealth study targeting HIV+ men who have sex with men (MSM).

Project Terms:
Address; Adolescent; Adopted; Advertising; Affect; AIDS/HIV problem; Algorithms; antiretroviral therapy; arm; Assessment tool; base; Behavior; behavior influence; Businesses; Capital; Caring; Characteristics; Charge; cognitive process; cohesion; Collection; Commercial Sectors; Communication; Communities; consumer behavior; Country; Custom; dashboard; Data; Data Set; Demographic Factors; demographics; design; Development; Diagnosis; Drug usage; effective intervention; Effectiveness; eHealth; Eligibility Determination; Enrollment; Environment and Public Health; Evaluation Research; evidence base; extravert; Face; Funding; Health; health organization; Health Professional; high risk; HIV; Human Resources; improved; Individual; innovation; insight; instrument; interest; Intervention; Interview; Libraries; Marketing; Measures; men who have sex with men; Methodology; Methods; Minority; Morbidity - disease rate; Neurotic Disorders; Nonprofit Organizations; Online Systems; Outcome; outreach; Participant; Personal Satisfaction; Personality Assessment; personalized approach; Pharmaceutical Preparations; Phase; Politics; Population; population health; Preventive Intervention; Process; programs; prototype; Public Health; public health intervention; public health research; Publishing; Questionnaires; recruit; Reproductive Health; Research; Research Personnel; research study; Resources; response; Risk Behaviors; Sampling; Small Business Innovation Research Grant; social; social stigma; STI prevention; Stratification; Subgroup; success; Surveys; System; Target Populations; Techniques; Testing; therapy adherence; Time; tool; trait; Translating; treatment arm; Typology; United States National Institutes of Health; volunteer; Work;

Successfully reaching and enrolling fully representative target populations in public health interventions is a highly desired, but notoriously difficult, prospect, especially when an initiative is focused on socially charged issues or health conditions that affect vulnerable subgroups. For example, HIV/AIDS has disproportionately high morbidity among a number of minority/marginalized populations, and faces a stigma that further complicates recruitment efforts. The commercial sector, on the other hand, faces similar challenges for engaging diverse audiences, but has achieved highly notable successes in its marketing and advertising efforts. Brands and companies have effectively utilized a number of innovative approaches to increase operational efficiency, measure campaign effectiveness, and capture relevant data to pinpoint specific consumer behavior. A comparable approach, tailored to meet the idiosyncratic needs of the public health enterprise, would offer significant improvement to its ability to engage with intended audiences. Those proven methods, however, entail significant capital and dedicated personnel that are not typically available to the majority of public health organizations. Thus, there is a pronounced yet unmet need for more scalable toolsets that can improve outreach and engagement of target populations. In order to address these challenges, this project seeks to increase representative enrollment through customized outreach analyses and informed tailoring of recruitment and engagement strategies. The proposed web-based system will enable researchers to conduct typology stratification of participant groups based on demographic, psychographic, and other pertinent characteristics, and will provide a platform for iterative improvement toward encouraging desired enrollee behavior in real-time. This targeted approach holds the promise to enhance participant engagement in public health interventions, and will be tested in the context of facilitating enrollment in an eHealth study targeting HIV+ men who have sex with men (MSM).

Public Health Relevance Statement:
PROJECT NARRATIVE Outreach campaigns that are tailored to recipient characteristics has proven highly impactful in engaging target populations. When executed sufficiently, they can facilitate greater representativeness in public health research studies and programs. However, the process of developing and validating targeted campaigns is both time- and resource-intensive; the limited availability of funding and manpower within the public health environment necessitates more affordable tools that are highly automated and scalable. Successful development and dissemination of such tools, as exemplified in the envisioned Strata system, can meaningfully contribute to greater inclusiveness, reduced selection and volunteer biases, higher generalizability, and better population health outcomes.

NIH Spending Category:
Behavioral and Social Science; Bioengineering; Clinical Research; Clinical Trials and Supportive Activities; Health Disparities; Health Services; Infectious Diseases; Minority Health; Precision Medicine; Prevention; Sexual and Gender Minorities (SGM/LGBT*)

Project Terms:
Address; Adolescent; Adopted; Advertising; Affect; AIDS/HIV problem; Algorithms; antiretroviral therapy; arm; Assessment tool; base; Behavior; behavior influence; Businesses; Capital; Caring; Characteristics; Charge; cognitive process; cohesion; Collection; Commercial Sectors; Communication; Communities; consumer behavior; Country; Custom; dashboard; Data; Data Set; Demographic Factors; demographics; design; Development; Diagnosis; Drug usage; effective intervention; Effectiveness; eHealth; Eligibility Determination; Enrollment; Environment and Public Health; Evaluation Research; evidence base; extravert; Face; Funding; Health; health organization; Health Professional; high risk; HIV; Human Resources; improved; Individual; innovation; insight; instrument; interest; Intervention; Interview; Libraries; Marketing; Measures; men who have sex with men; Methodology; Methods; Minority; Morbidity - disease rate; Neurotic Disorders; Nonprofit Organizations; Online Systems; Outcome; outreach; Participant; Personal Satisfaction; Personality Assessment; personalized approach; Pharmaceutical Preparations; Phase; Politics; Population; population health; Preventive Intervention; Process; programs; prototype; Public Health; public health intervention; public health research; Publishing; Questionnaires; recruit; Reproductive Health; Research; Research Personnel; research study; Resources; response; Risk Behaviors; Sampling; Small Business Innovation Research Grant; social; social stigma; STI prevention; Stratification; Subgroup; success; Surveys; System; Target Populations; Techniques; Testing; therapy adherence; Time; tool; trait; Translating; treatment arm; Typology; United States National Institutes of Health; volunteer; Work