Phase II year
2017
(last award dollars: 2018)
Phase II Amount
$1,491,382
There is a tremendous need for tools that allow NIH sponsored investigators to easily share and disseminate data from brain imaging studies. Access to large neuroimaging data sets is a critical aspect of learning about how the brain works both in health and disease. Most typically, large data sets are collected by one investigator, used for a specific purpose, and then archived. Sometimes these data are shared with collaborators, typically after an extended effort. Such an approach takes a very narrow view of what could be learned from these rich data sets. For example, there are often multiple questions that could be asked but werent conceived at the time of the study design. There are also a plethora of advanced analytic techniques and approaches, developed by multiple groups, which can be applied to these data to identify hidden structure or answer new questions. However, there are many barriers to data sharing of multimodal neuroimaging data and the community has tried for years to confront the various barriers. In this direct Phase II SBIR we are proposing a unique approach which is to take the neuroinformatics tools that we have been developing at the Mind Research Network and create a user friendly neuroinformatics suite which will enable prospective management and sharing of studies, assessments, and neuroimaging data. Investigator tools allow management of privacy within prospective (ongoing) studies. These tools allow investigators to control what is shared with collaborators. We believe that robust privacy controls are essential for data sharing. All data is collected, stored, and managed within a scalable infrastructure. We will deliver our neuroinformatics suite to NIH sponsored investigators, as well as other customers and clients. The rollout process and implementation includes installation, support, training, and data storage. The successful completion of this project would represent a major transformation which could propel scientific sharing and knowledge extraction of diverse types of data into a practical and widely used model.
Public Health Relevance Statement: Project Narrative There is an immediate need for tools to easily share and disseminate data from brain imaging studies. Previous and ongoing attempts do not handle prospective collection of all data and require a significant customization effort to implement at existing sites. We are proposing to deliver an intuitive neuroinformatics suite which can handle all aspects of study data collection, management of security, and data sharing.
Project Terms: Adopted; Adoption; Archives; Assimilations; base; Behavioral; Biological Markers; biomedical informatics; Brain; Brain imaging; Businesses; Case Report Form; Client; Clinical Data; Clinical Trials; cloud based; Cloud Service; Collection; commercialization; Common Data Element; Communities; Computer software; cost; Custom; Data; Data Collection; data management; Data Set; Data Sources; Data Storage and Retrieval; database of Genotypes and Phenotypes; Disease; Elements; Ensure; Event; experience; Funding; Genetic; Goals; Government; Growth; Health; Image; Imaging Device; imaging genetics; imaging study; Informatics; interoperability; Intuition; Journals; Knowledge Extraction; Label; Learning; Letters; Linux; Maintenance; Maps; Measures; Methods; Mind-Body Method; Modality; Modeling; Monitor; multimodality; neuroimaging; neuroinformatics; Online Systems; Operating System; Phase; Phenotype; Positioning Attribute; pressure; Privacy; Process; prospective; Provider; quality assurance; Reading; Regulation; repository; Research; Research Design; Research Domain Criteria; Research Infrastructure; Research Personnel; research study; Running; Security; Services; sharing data; Site; Small Business Innovation Research Grant; social media; Source; Staging; statistics; Structure; Sulfur; symposium; Techniques; Terminology; Time; Time Study; tool; Training; United States National Institutes of Health; user-friendly; Validation; virtual; web services; web site; web-based tool; Work
