SBIR-STTR Award

Cams Relational Agent System (CAMS-RAS) for Suicide Prevention
Award last edited on: 3/3/2021

Sponsored Program
SBIR
Awarding Agency
NIH : NIMH
Total Award Amount
$3,153,405
Award Phase
2
Solicitation Topic Code
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Principal Investigator
Linda A Dimeff

Company Information

Evidence-Based Practice Institute LLC

3303 South Irving Street
Seattle, WA 98144
   (206) 265-2507
   support@ebpi.org
   www.practiceground.org
Location: Single
Congr. District: 09
County: King

Phase I

Contract Number: 1R43MH108222-01A1
Start Date: 12/18/2015    Completed: 12/17/2016
Phase I year
2016
Phase I Amount
$274,259
Every 13 minutes, someone in the United States (U.S.) chooses to end his or her life, resulting in over 40,000 suicides in the US each year. The economic cost of suicide in the U.S. was $34.6 billion annually in 2005; when adjusted for present day inflation, the economic toll rises to $42.2 billion. The combined cost of medical and work loss is estimated at $34.6 billion annually. In 2011, 487,700 people were treated in EDs for self-inflicted injuries. Beginning in 1999 with the Surgeon General's Call to Action to Prevent Suicide, millions have been devoted annually - both publicly (approximately $40 million from NIH) and privately (approximately $20 million from American Foundation for Suicide Prevention) - to prevent suicide. Yet, despite this significant and sustained effort, there is no evidence of a decrease in suicides or suicide attempts in the U.S. Our overarching goal is to create a tool that could reduce suicide rates, increase delivery of efficacious suicide interventions, and decrease overall costs associated with suicidal behaviors. With this in mind, we intend to: (1) develop and scientifically validate a relational agent for suicidal patients that delivers Collaborative Assessment and Management of Suicidality (CAMS), an efficacious and cost-effective intervention developed by David Jobes, PhD; and (2) to create an integrated software system (CAMS Relational Agent System; CAMS-RAS) that assists medical personnel by synthesizing the CAMS intervention findings into an easy-to-interpret report and providing empirically-derived clinical decision support; integrates into the health care system's electronic health record (EHR); enhances the patient's coping capability by including psychoeducational skills training modules for use during and after hospitalization; and automates the delivery of caring contacts, an efficacious and brief suicide prevention intervention provided after discharge. Our initial target will be EDs, as they are often the initial point of contact and where personnel must make the decision whether to hospitalize or discharge the suicidal patient. We will also conduct testing in other medical and outpatient mental health settings to ensure public health impact and commercial success. Phase I project aims include: (1) creating an advisory board to guide the development of CAMS-RAS; (2) iteratively design and develop relational agent ("Dr. Dave") modeled after the gestures, expressions, and mannerisms of CAMS treatment developer, David Jobes, PhD; and (3) conduct feasibility tests to determine whether CAMS-RAS is acceptable, easy to use, and liked by target end-users: acutely suicidal patients admitted to hospital EDs, psychiatric inpatient units, and medical floors for treatment of injuries sustained during a suicid attempt; hospital medical personnel, administrators, and other stakeholders including peer advocates; and outpatient suicidal patients, clinicians and administrators.

Public Health Relevance Statement:


Public Health Relevance:
Suicide is the tenth leading cause of death among Americans of all ages. Over 40,600 suicides occurred in the U.S. in 2012 - one suicide every 13 minutes. In the same year, over a million U.S adults reported attempting suicide; 483,596 were treated in emergency departments (EDs) for self-inflicted injuries, and 332,833 were hospitalized. The cost of suicidal behaviors in the U.S. was $33 billion in 2012. The Collaborative Assessment and Management of Suicidality (CAMS) is an evidence-based, cost-effective, suicide-specific intervention that facilitates engagement, assessment, and treatment of suicidal risk. Unfortunately, most ED and outpatient mental health clinicians do not know CAMS and lack knowledge in how to effectively assess and intervene with suicidal individuals. The CAMS Relational Agent System seeks to facilitate the delivery of CAMS and other evidence-based procedures to reduce suicide.

Project Terms:
Accident and Emergency department; Administrator; Adult; Advocate; Age; Ambulatory Care Facilities; American; base; care delivery; Caring; Cause of Death; Client; Clinic; Clinical; commercialization; coping; cost; cost effective; cost effectiveness; Decision Making; design; Development; Doctor of Philosophy; economic cost; Economic Inflation; Educational workshop; effective intervention; Electronic Health Record; Elements; Ensure; Event; evidence base; Feeling hopeless; Feeling suicidal; Floor; formative assessment; Foundations; Gestures; Goals; Health; Health Personnel; Healthcare Systems; Hospital Departments; Hospital Readmission; Hospitalization; Hospitals; Human; Human Resources; improved; Injury; innovative technologies; Inpatients; Intervention; Knowledge; Life; Medical; Mental disorders; Mental Health; Mind; Modeling; Names; National Institute of Mental Health (U.S.); Nurses; Outcome; Outpatients; Patients; peer; Phase; phase 1 study; Physicians; prevent; Preventive Intervention; Procedures; prototype; Provider; Psychiatry; psychoeducational; public health medicine (field); public health relevance; Randomized Controlled Trials; reducing suicide; Reporting; Risk Assessment; Risk Management; satisfaction; Self Efficacy; skills training; software systems; success; suicidal; suicidal behavior; suicidal individual; suicidal patient; suicidal risk; Suicide; Suicide attempt; Suicide prevention; suicide rate; Surgeon; System; Testing; tool; Training; Training Activity; trial comparing; United States; United States Agency for Healthcare Research and Quality; United States National Institutes of Health; usability; Vision; Work

Phase II

Contract Number: 2R44MH108222-02A1
Start Date: 12/18/2015    Completed: 2/28/2021
Phase II year
2018
(last award dollars: 2020)
Phase II Amount
$2,879,146

Over 44,000 people die annually by suicide in the United States (US) making suicide the 10th leading cause of death overall and the second leading cause of death among those 10-44. In addition, 9.8 million adults contemplate suicide annually, and one million will make a suicide attempt. From 2006 to 2013, the rate of ED visits for suicidal ideation among adults increased by 12% on average annually. While millions are devoted annually to prevent suicide, suicide rates are rising in the US. Our ultimate aim is to reduce deaths by suicide while also reducing unnecessary hospitalization, emergency department (ED) and hospital readmissions, and stop the revolving-door of acute crisis care through the use of innovative technologies. In Phase I, we proposed to: (1) develop and scientifically validate an avatar for use by suicidal ED patients that delivers the Collaborative Assessment and Management of Suicidality (CAMS), an efficacious and cost-effective intervention developed by David Jobes, PhD; and (2) to design clinical support tools and Just-in- Time training for use by ED medical providers to enhance their delivery of an evidence-based suicide protocol and facilitate an evidence-based approach to discharge disposition. Our work was also guided by Phase I reviewers? concerns. We fully met and exceeded project aims. Most notably, we created a 15-minute avatar (?Dr. Dave?) who performed a portion of the CAMS Suicide Status Interview which was well-liked and described as helpful by suicidal ED patients who interacted with ?Dr. Dave.? In Phase II, we propose to complete the development of Virtual CAMS patient and provider tools and to ready it for EHR integration into EPIC. We will again use an agile process of development and seek feedback from target end-users. A diverse group of advisors will consult to us to ensure product excellence and readiness for commercialization. To ensure thorough testing of the product?s provider and patient tools, we will use a two-condition, randomized study to evaluate Virtual CAMS? efficacy in preventing suicidal behaviors and inappropriate/unnecessary hospital admissions, and improving self-efficacy for coping with acute distress.

Thesaurus Terms:
Accident And Emergency Department; Acute; Administrator; Admission Activity; Adult; Advocate; Age; American; Base; Behavioral; Boston; Brief Intervention; Caring; Cause Of Death; Clinical; Clinical Decision Support; Commercialization; Consult; Coping; Coping Skills; Cost Effective; Design; Development; Distress; Doctor Of Philosophy; Economic Cost; Effective Intervention; Electronic Health Record; Emergency Department Patient; Emergency Department Visit; Ensure; Evidence Base; Evidence Based Practice; Experience; Feedback; Feeling Suicidal; Future; Health Personnel; Healthcare; Healthcare Systems; Hospital Departments; Hospital Readmission; Hospitalization; Hospitals; Human; Improved; Innovative Technologies; Intervention; Interview; Marketing; Medical; Nurses; Occupations; Participant; Patients; Peer; Phase; Physicians; Policies; Positioning Attribute; Prevent; Privatization; Procedures; Process; Protocols Documentation; Provider; Public Health Relevance; Randomized; Randomized Controlled Trials; Readiness; Recruit; Reducing Suicide; Reporting; Research; Risk Assessment; Self Efficacy; Success; Suicidal; Suicidal Behavior; Suicidal Morbidity; Suicidal Patient; Suicidal Risk; Suicide; Suicide Attempt; Suicide Prevention; Suicide Rate; Support Tools; Surgeon; System; Testing; Time; Tool; Training; United States; Universities; Usability; Virtual; Work;