Base5 Biosciences is a biotechnology research company developing tools for studying RNA methylation and demethylation pathways. Having extensive backgrounds in RNA epigenetics, the founding researchers were among the first to discover that adenosine methylation (m6A) is a widespread modification in cellular mRNAs. Structured around development of the first antibody-based methods for global N6-methyladenosine (m6A) mapping and consistently at the forefront of m6A research, the primary research goals of Base5 are to develop novel tools for the identification and quantification of m6A within individual RNAs and to utilize innovative high-throughput screening assays to identify inhibitors of m6A demethylases.
