Date: Apr 15, 2013 Source: Company Data (
click here to go to the source)
A recent publication in Proceedings of the National Academy of Sciences showed that 3D polymer scaffolds better recapitulate the tumors growth microenvironment as compared with two-dimensional plastic surfaces typically used in cancer research for testing anti-cancer drugs, according to researchers at Rice University, the University of Texas MD Anderson Cancer Center, and Mount Sinai Medical Center. "The tumor growth profile and protein expression characteristics were "remarkably unlike" those in 2-D," according to Prof. Mikos, one of the co-authors of the publication. According to those researchers, porous polycaprolactone (PCL) nano-fiber polymer scaffolds fabricated to support the growth of biological tissue for tissue engineering hold the potential to greatly accelerate the development of cancer drugs.
3D Biotek has been developing 3D polymer scaffolds for drug screening and tissue engineering applications. The 3D Insert-PCL with Nanomesh has been developed by combining the benefits of PCL nanofibers and micro-scale 3D scaffold structure to provide a unique feature for use in tumor and stem cell research. Our 3D scaffold products are available from our world-wide distributors, including Sigma-Aldrich.
