Originally anchored in modeling and simulation, in software, test and evaluation,engineering, data science and design services, in common with several other long-term (and early) SBIR involved firms, CFD Research (CFD Research Corporation) became program active coincident with founding and has remained fully involved over the now several decades of SBIR operations. Specializing in engineering simulations and innovative designs appicable inmany arenas - aerospace, biomedical, defense, materials, energy, etc - the firm's personnel are adept at using developed software and experimental facilities to yield new hardware concepts, innovative designs, and prototypes. With a substantial patent portfolio - awarded or pending - in areas as diverse as biotechnology, combustion, propulsion, and materials, the firm's capabilities allow coupled multiscale, multiphysics simulations of fluid, thermal, chemical, biological, electrical, and mechanical phenomena for real-world applications. Such simulations provide insights into complex systems, enabling better decisions and facilitating better products with lower risk, reduced cost, and less time.